Built in 1874 on the hillside of Hermoupolis and officially designated a cultural monument by the Greek Ministry of Culture, Palazzo Santa Maria is a neoclassical mansion restored with deep personal passion by its owner of five decades’ hospitality experience. Six rooms and suites — named after legendary guests with ties to Syros, from Sarah Bernhardt to Maria Callas — feature original frescoes, antique furnishings, and a hand-curated art collection evoking the island’s 19th-century Golden Era.